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Education
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Aug.
2006 - present
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Ph.D.
Student, Electrical and Computer Engineering, Virginia Tech
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Sept.
2003 - Feb. 2006
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M.S.,
Department of Automation, Shanghai Jiao Tong University
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Sept.
1999 - July 2003
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B.S.,
Department of Control Science and Engineering, Huazhong University
of Science & Technology
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[Top]
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Statistical Machine Learning and
its application on biomedical sciences
Computational biology
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- Genome-wide
association study: Single-nucleotide polymorphism (SNP) screening,
epistatic
SNP detection
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- expression Quantitative Trait Locus (eQTL)
mapping
- Other applications on computational biology: gene
expression, copy number variation and etc.
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Biomedical image analysis and
computer vision
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- Image
analysis, blind source separation and pharmacokinetic analysis on Dynamic
Contrast Enhanced Magnetic Resonance imaging (DCE-MRI)
- Image
segmentation, image enhancement, and other traditional computer vision
problem
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Journal Publications
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Computational
biology
W. Liu, S. Laitinen, S. Khan, M. Vihinen, J. Kowalski, G.
Yu, Li Chen, S.
Yegnasubramanian, J. Luo, Yue Wang, J. Xu, W. B. Isaacs, T. Visakorpi,
and G. Bova, "Copy Number Analysis Indicates Monoclonal Origin of
Lethal Metastatic Prostate Cancer," Nature Medicine,
vol. 15, no. 5, pp. 559-565, 2009.
D. J. Miller, Y. Zhang, G. Yu, Y. Liu, Li Chen, C. D. Langefeld, D. Herrington, and Yue Wang,
"An Algorithm for Learning Maximum Entropy Probability Models of
Disease Risk That Efficiently Searches and Sparingly Encodes Multilocus
Genomic Interactions," Bioinformatics, Jun. 2009.
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Image analysis &
Computer Vision
Li Chen, Yue Zhou and
Yong-Gang Wang, "GACV: Geodesic-aided C-V method", Pattern Recognition, vol.
21, pp. 1391-1395, 2005.
Li Chen, Yue Zhou and
Yong-Gang Wang, "Unsupervised C-V method in halftone image
segmentation", Computer Engineering, Sept., 2006.
Lei Yang, Yue Zhou, Jie Yang and Li Chen, "Variance WIE based infrared image processing, "
Electronics Letters, vol. 44, pp. 857-859, 2006.
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Conference
Publications
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Computational biology
Li
Chen, Guoqiang Yu, David Miller, Lei Song, Carl
Langefeld, David Herrington, Yongmei Liu, and Yue Wang, "A Ground
Truth Based Comparative Study on Detecting Epistatic SNPs", to
appear in Proc. The 2009
Applications of Machine Learning in Bioinformatics Workshop, Washington D.C., USA, Nov. 2009.
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Image analysis & Computer Vision
Li Chen, T.-H. Chan, P. L. Choyke,
C.-Y. Chi, G. Wang, and Y. Wang, "Convex Analysis and Separation of
Composite Signals in DCE-MRI," Proc.
5th IEEE Intl Symposium on Biomedical Imaging: From Nano to Macro, Paris, France, May 2008.
Li Chen, Y. Wang, C.-Y. Chi, Z. Szabo,
and P. L. Choyke, "Separating composite signals in multi-probe
dynamic biomedical imaging," Proc.
41st Annual Asilomar Conference on Signals, Systems, and Computers,
Pacific Grove, CA, Nov. 2007.
Li Chen, Yue Zhou and Yong-Gang Wang, "A novel color C-V method and its
application, Lecture Notes in Computer Science",
ICIAR'05, vol.3656, pp. 40-47, 2005.
Patent
Li
Chen, Yue Zhou, An active contour based method for halftone image
segmentation (2006 in China)
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I like
music, sports, reading, movie, cartoon, karaoke, and all kinds of
interesting things.
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